From DHV ….by The Editors
Cannabis against common diseases
The “Cannabis as Medicine” law currently allows the use of cannabinoids as medicine for seriously ill patients. A variety of ailments can be treated successfully with cannabis and increasing scientific studies on the subject deal with the therapeutic efficacy of cannabinoids. Therefore, we have for you the five most common diseases in which cannabis could be used.
1. Back Pain
In Germany statistically currently 32-49% of people back pain. Approximately 70% have pain at least once a year and about 80% complain at least once in a lifetime of backache ( Source: Robert Koch Institute ).
In the majority of patients, this is not due to unique causes. Spasms and inflammation caused by faults within the complex working of the muscles, joints and ligaments of the back.
Studies on the use of cannabinoids in chronic pain show a possible application in pain medicine. Interesting for the pain therapy in this context are the two best known cannabinoids, the psychoactive THC (tetrahydrocannabinol), and the little psychoactive CBD (cannabidiol). Cannabinoids are to alleviate the situation, back pain and muscle spasms. Loosen cramps in the muscles, acting analgesic and anti-inflammatory.
The endocannabinoid system is a part of the nervous system and consists of receptors that control, among other things, the mood, appetite, digestion and pain. At these receptors dock at the cannabinoids of the cannabis plant. THC binds to the two known cannabinoid receptors CB1 and CB2. The CB1 receptor is one of the most common receptors in the brain and also occurs in most other tissues and organs of the body. If the CB1 receptor is activated by THC, so it causes, in addition to numerous other effects, pain relief and muscle relaxation. Excessive activity in the pain circuits of the brain is inhibited, thereby alleviating the pain. The CB2 receptor is found mainly on the immune cells. Activation of the CB2 receptor by THC inhibits inter alia inflammation.
According to the Robert Koch Institute about suffering 25 percent of the German population from insomnia.
“The possible sleep-inducing effects of cannabis have been known for a long time. Dr. Bernhard Fronmüller, doctor at the hospital in Fürth and royal Bavarian district physician, reported in 1869 in his acclaimed work “Clinical studies on the sleep-making effect of the narcotic drug” about his experiences at exactly one thousand patients suffering from different causes of severe insomnia and had been treated by him with various medications. After cannabis was in 53 percent of cases, good effect, little or no effect in 21.5 percent partially and 25.5 percent “(Dr. Franjo Grotenhermen:.. Cannabis and THC in severe insomnia )
THC has on the body an artery widening effect. The enlargement of the blood vessels, the blood pressure is lowered and as a result also reduces the body temperature. It comes to a feeling of relaxation and stress reduction. This can, of course, conducive to sleep depth and duration of effect.
In Germany 20-25% of the population suffers from allergic disease. 86% of all allergies have a pollen allergy, 41% are allergic to dog or cat, 38% of house dust and 14% to molds (source: German Society for Allergology and Clinical Immunology ).
A study by the University of Bonn from 2007 has shown that cannabinoids have anti-inflammatory properties. In the experiment with mice applying reduced a THC solution allergic skin reaction demonstrably. The endocannabinoid system plays an important role in the regulation of inflammatory processes in the body. The cannabinoid THC bind to cannabinoid receptors and activates them. Characterized the allergic response is reduced. For example, contact allergies with hemp ointment can be treated successfully. Even patients with allergic asthma have reported relief from their symptoms through medication with cannabis.
Migraine is one of the most common forms of headache, around 10 percent of the adult population in Germany suffers from migraine attacks (Source: German Society of Neurology ).
Medical marijuana may successful in the treatment of migraine may be used. A study by the University of Colorado has researched the effects of medical marijuana on the frequency of migraine attacks. But were 121 adults, in which migraine headaches were diagnosed and where medical marijuana by a doctor had prescribed, examined in the period from January 2010 to September 2014. The effects were significant. In 85 percent of cases, the patients experienced a decrease in headaches from an average of 10.4 to 4.6 times a month. With 12 percent of the participants the complaints heard even on quite.
The causes of migraine are varied and still controversial. Thus previous studies have chronic migraines with a malfunction in the endocannabinoid system brought the persons concerned in relation. It is understood in this context the fact that cannabinoids reduce the pain associated with migraine, by controlling the penetration of the pain signals to the brain through the receptors of the endocannabinoid system.
Another effect of cannabis on the body is the already mentioned expansion of blood vessels. As a possible cause of migraines and circulatory disorders in the brain play a role cannabis may also help alleviate. So let the vasodilator effects that acts cannabis on meninges, subside a migraine attack. Migraine attacks are also often accompanied by severe nausea. Cannabis helps not least here, too. Cannabinoids attributed a sickness and nausea-suppressing effect.
According to the Foundation German Depression Help about 5% of the population suffers aged 18-65 years in Germany develops major depression. Almost one in five ill at least once in their lives from depression. (18 percent of the population). Thus, depression is one of the largest common diseases.
One of the best known properties of cannabis is its antidepressant effects, which may suffering from depression people benefit. In particularly interesting therapeutic point here is the mode of action of cannabidiol (CBD shortly). These writes Dr. Franjo Grothenhermen : “Animal studies with rats and mice do not support previously published patient experience that CBD has antidepressant properties. So researchers at the University of Cantabria (Spain) found in two studies of a mouse model of depression found that “CBD could represent a new, fast-acting drug by both signaling pathways in the cerebral cortex that respond to serotonin or glutamate, by a 5 -HT1A receptor dependent mechanism strengthened. “
View and potential:
Overweight and obesity
Slightly more than half of women (53%) and two thirds of men (67%) in Germany are overweight . About a quarter of adults is even very overweight (obese). Overweight and obesity are mainly responsible for a variety of complications.
Cannabis contains a variety of different cannabinoids, including not only the known appetizing ingredients. The cannabinoid CBD could assist in combating obesity help. Thus CBD plays a role in the so-called browning white fat cells. In the human body there are two different types of fat cells. Firstly, the so-called “white fat cells”, which contribute substantially to the formation of fatty deposits and secondly, the “brown fat cells”, which are able to convert excess energy into heat. The conversion of white adipocytes to brown adipocytes (tanning) and the activation of existing brown fat cells are currently investigated as ways to combat obesity.
“The scientists showed that CBD might have a role in the browning of white fat cells, in enhancing the fat burning in heat production and in reducing the fat production. They wrote that “CBD could be explored as a potential promising therapeutic agent for the prevention of obesity” (Franjo Grotenhermen: new in science to the treatment with CBD ) “Here the research is still at its infancy and we are excited. , how it goes on.
This post may be considered in no way intended to replace professional medical care by a qualified practitioner. The information should not be used to independently provide diagnosis or treatment.